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Research topics

Research topics


workpackage1

Chassis strain engineering for e.cient gas
feedstock conversion

workpackage1

Hydrogen-driven whole-cell biotransformations

workpackage1

Process intensiFcation of gas-driven processes

Chassis strain engineering for e.cient gas
feedstock conversion

The objective of WP1 is to provide an optimized strain for the conversion of the gas feedstock by metabolic engineering, flux analysis and the engineering of transport systems. The design of molecular genetic tools and the comprehensive characterization of selected strains will be essential.


ESR1: Synthetic biology to streamline the metabolism of C. necator toward the production of rare amino acids and proteins

1st Supervisor: Dr. Sandy Schmidt
2nd Supervisor: Prof. Lars M. Blank
University of Groningen

ESR2: Metabolic strategies for the synthesis of isotope-labeled amino acids in C. necator

1st Supervisor: Dr. Sandy Schmidt
2nd Supervisor: Dr. Lars Lauterbach
University of Groningen

ESR3: Metabolic Engineering of C. necator to exploid lipid de novo synthesis for OH-fattyacid ester production

1st Supervisor: Prof. Lars M. Blank
2nd Supervisor: Dr. Sandy Schmidt
RWTH Aachen

ESR4: Transport engineering in C. necator

1st Supervisor: Prof. Robert Kourist
2nd Supervisor: Dr. Stéphane Guillouet
acib GmbH

Chassis strain engineering for e.cient gas
feedstock conversion

The objective of WP1 is to provide an optimized strain for the conversion of the gas feedstock by metabolic engineering, flux analysis and the engineering of transport systems. The design of molecular genetic tools and the comprehensive characterization of selected strains will be essential.


ESR1: Synthetic biology to streamline the metabolism of C. necator toward the production of rare amino acids and proteins

1st Supervisor: Dr. Sandy Schmidt
2nd Supervisor: Prof. Lars M. Blank
University of Groningen

ESR2: Metabolic strategies for the synthesis of isotope-labeled amino acids in C. necator

1st Supervisor: Dr. Sandy Schmidt
2nd Supervisor: Dr. Lars Lauterbach
University of Groningen

ESR3: Metabolic Engineering of C. necator to exploid lipid de novo synthesis for OH-fattyacid ester production

1st Supervisor: Prof. Lars M. Blank
2nd Supervisor: Dr. Sandy Schmidt
RWTH Aachen

ESR4: Transport engineering in C. necator

1st Supervisor: Prof. Robert Kourist
2nd Supervisor: Dr. Stéphane Guillouet
acib GmbH

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